Review of Clinical Trials Evaluating Safety and Efficacy of Milk Thistle (Silybum marianum [L.] Gaertn.)

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Milk Thistle (Silybum marianum)

Milk thistle is a well known and commonly used herb, used particularly in hepatic diseases. It has very potent antioxidant, anti-inflammatory, and antifibrotic properties (1). As a single agent its therapeutic effects in liver disease appear to be modest (2,3,4,5). Herbal medicines and supplements are likely to be much more beneficial when used synergistically in combinations or formulas. Milk ...

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A Review on Pharmacological, Cultivation and Biotechnology Aspects of Milk Thistle (Silybum marianum (L.) Gaertn.)

Milk thistle (Silybum marianum (L.) Gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. The major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of three isomer silybin, silydianin and silycristin. Its therapeutic properties are due to the presence of silymarin. The seeds contain the highest a...

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Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)

Use of the herb milk thistle (Silybum marianum) is widespread, and its chemistry has been studied for over 50 years. However, milk thistle endophytes have not been studied previously for their fungal and chemical diversity. We examined the fungal endophytes inhabiting this medicinal herb to determine: (1) species composition and phylogenetic diversity of fungal endophytes; (2) chemical diversit...

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a review on pharmacological, cultivation and biotechnology aspects of milk thistle (silybum marianum (l.) gaertn.)

milk thistle (silybum marianum (l.) gaertn.) is one of the valuable medicinal plants which used in the treatment of liver disorders. the major active constituents in this plant are flavonolignans, collectively known as silymarin which is a mixture of three isomer silybin, silydianin and silycristin. its therapeutic properties are due to the presence of silymarin. the seeds contain the highest a...

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Antioxidant Activity of Flavolignans from Silybum marianum (L). Gaertn. Fruits

The flavolignans silybin (1) and 2,3-dehydrosilybin (2) (Figure 1) were isolated from fruits of milk thistle [Silybum marianum (L). Gaertn.] cultivated in the Samara region (Russian Federation). 2,3-dehydrosilybin (2) for the first time in Russian Federation is described for the given plant. Silybin and 2,3-dehydrosilybin and also new preparation, a fluid extract of Silybum marianum fruits, hav...

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ژورنال

عنوان ژورنال: Integrative Cancer Therapies

سال: 2007

ISSN: 1534-7354,1552-695X

DOI: 10.1177/1534735407301942